Mg2+-driven selection of natural phosphatidic acids in primitive membranes
Thaipurayil Madanan K., Li Y., Boide-Trujillo V. J., Russell D. A., Bonfio C. ChemRxiv (2024).
Nonenzymatic autocatalysis generates coacervates and controls their structure
Mihoubi F. Z., Nakashima K., Bonfio C. Chem (2023), 9, 3394-3396.
Ring opening of glycerol cyclic phosphates leads to a diverse array of potentially prebiotic phospholipids
Aleksandrova M., Rahmatova F., Russell D. A., Bonfio C.* Journal of the American Chemical Society (2023), 145, 25614-25620.
Interfacing coacervates with membranes: from artificial organelles and hybrid protocells to intracellular delivery
Lu T., Javed S., Bonfio C., Spruijt E. Small Methods (2023), 2300294.
Bioenergetics of early life
Aleksandrova M., Bonfio C.* EMBO Reports (2022), e55679.
A possible path towards encoded protein synthesis on ancient Earth
Bonfio C.* Nature (2022), 605, 231-232, News&Views.
Thermally driven membrane phase transitions enable content reshuffling in primitive cells
Rubio-Sanchez R., Wang A., O’Flaherty D., Coscia F., Petris G., Di Michele L., Cicuta P., Bonfio C.* Journal of the American Chemical Society (2021), 143, 16589-16598.
The curious case of peptide-coordinated iron–sulfur clusters: prebiotic and biomimetic insights
Bonfio C.* Dalton Transactions (2021), 50, 801-807.
Choroid plexus organoids predict CNS drug permeability and reveal human CSF proteins produced by specialised cell types
Pellegrini L., Bonfio C., Chadwick J., Begum F., Skehel M., Lancaster M. Science (2020), 369, eaaz5626.
Activation chemistry drives the emergence of functionalised protocells
Bonfio C.*§, Russell D. A.§, Green N. J., Mariani A., Sutherland J. D. Chemical Science (2020), 11, 10688-10697.
Harnessing chemical energy for the activation and joining of prebiotic building blocks
Liu Z., Wu L., Xu J., Bonfio C., Russell D. A., Sutherland J. D. Nature Chemistry (2020), 12, 1023-1028.
Glycerol configurations of environmental GDGTs investigated using a selective sn2 ether cleavage protocol
Liu X., Russell D. A., Bonfio C., Summons R. E. Organic Geochemistry (2019), 128, 57-62.
Length-selective synthesis of diacylglycerol-phosphates through energy-dissipative cycling
Bonfio C.§, Caumes C.§, Duffy C.C.§, Patel B. H.§, Percivalle C.§, Tsanakopoulou M.§, Sutherland J.D. Journal of the American Chemical Society (2019), 141, 3934-3939.
Investigation of glutathione-derived electrostatic and hydrogen bonding interactions and their role in defining Grx5 [2Fe-2S] cluster stability, optical spectra and transfer chemistry
Sen S., Bonfio C., Mansy S. S., Cowan J. A. Journal of Biological Inorganic Chemistry (2018), 23 (2), 241-252.
pH-driven RNA strand separation under prebiotically plausible conditions
Mariani A., Bonfio C., Johnson C., Sutherland J. D. Biochemistry (2018), 57, 6382-6386.
Prebiotic iron-sulfur peptide catalysts generate a pH gradient across model membranes of late protocells
Bonfio C., Godino E., Corsini M., Fabrizi De Biani F., Guella G., Mansy S. S. Nature Catalysis (2018), 1, 616-623.
UV light-driven prebiotic synthesis of iron-sulfur clusters
Bonfio C., Valer L., Scintilla S., Shah S., Evans D. J., Jin L., Szostak J. W., Sasselov D. D., Sutherland J. D., Mansy S. S. Nature Chemistry (2017), 9, 1229-1234.
The chemical roots of iron-sulfur dependent metabolism
Bonfio C., Mansy S. S. Biochemistry (2017), 56, 5225-5226.
Cysteine containing dipeptides show a metal specificity that matches the composition of seawater
Belmonte L., Rossetto D., Forlin M., Scintilla S., Bonfio C., Mansy S. S. Physical Chemistry Chemical Physics (2016), 18, 20104-8.
Duplications of an iron-sulfur tripeptide leads to the formation of a protoferredoxin
Scintilla S., Bonfio C., Belmonte L., Forlin M., Rossetto D., Li J., Cowan J. A., Galliani A., Arnesano F., Assfalg M., Mansy S. S. Chemical Communications (2016), 52, 13456-13459.